She starred on the 1970s sitcom as Dee, the younger sister offering a steady stream of deadpan roasts of her big brother Roger “Raj” Thomas and his friends.

A family spokesperson said Spencer died Monday after battling cancer for several years. As Dee, she was a deadpan, wisecracking sister on What's Happening!! Spencer later became a veterinarian.

On Monday1, 2025, Danielle Spencer sadly passed away from stomach cancer. She was best known for her acting career in the late 1970s and 1980s, particularly for her role in ABC’s sitcom What’s Happening!