The reigning Supporters’ Shield champions take on the defending MLS Cup champions for the first and only time this season.

Lionel Messi and Rodrigo De Paul were left out of the Inter Miami starting lineup Saturday night for the home game against the Los Angeles Galaxy, but both were on the bench and available to play.

The Galaxy is having a season worth forgetting. Despite being less than a year removed from winning the MLS Cup, one of the ...