Who has the advantage at quarterback when Brock Purdy and the San Francisco 49ers (1-2) match up with Jacoby Brissett and the ...

On Sunday, the 49ers couldn't rob the Rams of hope. The trick now is to get it together fast enough so they don't lose their ...

The San Francisco 49ers have a next man up mentality. With Deebo Samuel out of the lineup, wide receiver Jauan Jennings was ...

Tensions flared at the end of the Los Angeles Rams' 27-24 win over the San Francisco 49ers on Sunday. After the final play of ...

Looking at Sunday’s New England Patriots at San Francisco 49ers Week 4 NFL odds, lines and trends. Here’s what you need to ...

Down 14-0 to the 49ers in the first quarter and 24-14 early in the fourth, they rally to win and may have proved something to ...

Here's where the San Francisco 49ers and the rest of the NFL stand in the latest power rankings heading into the Monday night ...

The Rams will also be without key players as star wideouts Cooper Kupp and Puka Nacua are both out; Nacua is on injured ...

The Rams defense forced two straight incompletions, then tackled 49ers quarterback Brock Purdy short. San Francisco (1-2) had ...

With Christian McCaffrey, Deebo Samuel and George Kittle already sidelined against the Los Angeles Rams, the injury bug ...

Brock Purdy laced a 13-yard pass to a wide open Jauan Jennings to get the 49ers on the board early against the Rams.

Joshua Karty hit a 37-yard field goal with 2 seconds to play, and the Los Angeles Rams staged a spectacular late rally for a ...