Cells, are you experiencing stress? Quick, SUMOylate your TDP-43 before it’s too late! Three independent papers appearing in rapid succession deliver the same message: Chain the small ubiquitin-like ...

Because hypertension is linked to a greater risk of dementia, several trials have investigated whether lowering blood pressure in older people would protect the brain. Data from cohorts of a few ...

At the AD/PD meeting held last month in Vienna, scientists implicated T lymphocytes—specifically, the cytotoxic, CD8-positive variety—in Alzheimer’s disease. While the modus operandi of these cells in ...

Converging evidence suggests that hearing loss during midlife increases a person’s odds of getting dementia. Now, research from Johns Hopkins’ Bloomberg School of Public Health, Baltimore, suggests ...

First trial of concurrent amyloid and tau immunotherapies in sporadic Alzheimer’s is underway. Safety data are a go for subcutaneous remternetug. Plaque removal correlates with cognitive benefit in ...

Undergraduate in psychology at UFCSPA.

Ph.D., SUNY Downstate Medical Center & NYS Institute for Basic Research, NY, USA. M.D., Aga Khan University, Karachi, Pakistan ...

The association between vaccination against the herpes zoster (HZ) virus, which causes shingles, and dementia risk continues to gain traction. Earlier this month, Pascal Geldsetzer and his team at ...

Talk about a closely watched study. Conference after conference, Roche scientists running the ongoing Brain Shuttle AD trial of trontinemab are dispensing morsels of news from sequential interim ...

For years, scientists have been working toward blood tests for Alzheimer’s disease that could be used routinely in clinical practice. Now, they are on the cusp. At this year’s ADPD conference, held ...

Tauopathies are a class of neurodegenerative disorders characterized by abnormal aggregation of the tau protein, encoded by the MAPT gene. These include frontotemporal dementia, Pick’s, and ...

In memory clinics and in research cohorts, immunoassays for plasma markers can now distinguish people who have Alzheimer’s disease pathology with remarkable accuracy (see Part 7 of this series). How ...