What is multiplex PCR? - Front Line Genomics
Jul 26, 2021 · The polymerase chain reaction (PCR) is a well-established amplification technique that is widely used to rapidly make millions of copies of a specific DNA sample. It was developed by Kary Mullis in the 1980’s and is based on the ability of DNA polymerase to synthesize a new strand of complementary DNA from a template strand.
Sample Preparation for NGS – A Comprehensive Guide
Aug 21, 2024 · Common challenges in sample preparation. Challenge 1: Many samples are extracted from a limited number of cells – or even a single cell.These don’t provide enough genetic material alone and so need to undergo PCR. However, this amplification step is prone to introducing bias to the sample.
The Festival of Genomics & Biodata 2025
Oct 15, 2024 · Bigger and better than ever before, The Festival of Genomics & Biodata is returning to London in January 2025! It’s hard to believe that the first Festival was 10 years ago, and it’s come a remarkably long way since then.
How to: perform polygenic risk score analysis
Jul 17, 2023 · A recent article highlights key issues related to polygenic risk score analyses and provides a starting point and reference guide for researchers.
Report: Liquid Biopsy 2024 - Front Line Genomics
ABOUT US CONTACT ADVERTISE PRIVACY POLICY Front Line Genomics Limited is registered in England and Wales. Company Number 10421716, VAT: GB 297 742 548. Registered Office: Ground Floor, Cromwell House, 15 …
How-to: perform a genome-wide association study (GWAS)
Sep 10, 2024 · Genome-wide association studies are commonly used in the genomics world to identify variants associated with a trait or disease.During a GWAS, researchers will identify areas of the genome that show a strong signal linked to the trait in question; that is, in the discovery cohort, areas or specific markers in which variation is more common than in the controls.
The Latest Developments in Sequencing Technologies
Feb 6, 2024 · Quantum-Si’s Platinum single-molecule protein sequencing platform works on digested individual peptides that are immobilized in wells. Fluorescently labelled N-terminal amino acid (NAA) recognizers then bind the individual peptides, and the resulting unique fluorescence signal is recorded onto a chip.
Report: The Single-cell and Spatial Playbook 2024
ABOUT US CONTACT ADVERTISE PRIVACY POLICY Front Line Genomics Limited is registered in England and Wales. Company Number 10421716, VAT: GB 297 742 548. Registered Office: Ground Floor, Cromwell House, 15 …
Long-read sequencing vs short-read sequencing
Jul 26, 2021 · Join David Smith (Mayo Clinic), Shawn Baker (SanDiegOmics) and Tiffany Boughtwood (Australian Genomics) as they discuss how the upcoming shifts within the NGS market could affect genomics research in the future and what impact it may have on healthcare around the world: Exploring the Current Sequencing Landscape Combining sequencing …
AI in Drug Discovery 2024: Where are we now?
Apr 3, 2024 · Back in 2020, we covered an industry analysis of the role of Artificial Intelligence in Drug Discovery. The report covered the period up to 2024 and suggested that the market was worth hundreds of millions of dollars. What’s going on in this field now that we’ve reached 2024?